Anti-human/monkey TNF-α mAb (MT21A8), unconjugated

Anti-human/monkey TNF-α mAb (MT21A8), unconjugated

3512M-3-250

Publications: 133
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Intended use

This monoclonal antibody enables specific detection of monkey TNF-α in immunoassays such as ELISpot, FluoroSpot, and ELISA.

Serum/Plasma samples

Recommendation

MT21A8 is recommended as capture mAb in ELISpot, FluoroSpot, and ELISA in combination with detection mAb MT15B15 (product code 3512M-6).

Product details

ProductAnti-human/monkey TNF-α mAb (MT21A8), unconjugated
ApplicationELISpot, FluoroSpot, ELISA
AnalyteTNF-α
AntibodyMT21A8
ConjugateUnconjugated
ClonalityMonoclonal
ImmunogenRecombinant human TNF-α
HostMouse
IsotypeIgG1
ReactivityNon-human primates, Human
Specificity

Native TNF-α from rhesus macaque and cynomolgus macaque. Native and recombinant human TNF-α.

Cross-reactivity

For information on reactivity with other non-human primates (NHP), please check the NHP cross-reactivity guide.

Purification

Purified from in vitro cultures by protein G affinity chromatography.

Concentration0.5 mg/ml
Supplied in

PBS with 0.02% sodium azide. Sterile-filtered (0.2 µm).

Contents

Monoclonal antibody MT21A8, unconjugated. Supplied at 0.5 mg/ml in PBS with 0.02% sodium azide.

Shipping and Storage

Shipping

Shipped at ambient temperature.

Storage

Store product at 4-8°C or frozen at -20°C or below. Avoid repeated freezing/thawing.

Shelf lifeAt least 18 months from date of receipt.

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TNF-α

Analyte description

Tumor necrosis factor (TNF), also known as TNF-α, is produced by many different cell types, e.g., monocytes, macrophages, T cells, and B cells. Among the many effects of TNF-α are protection against bacterial infection, cell growth modulation, immune system regulation, and involvement in septic shock.

Alternative namesTumor necrosis factor-α, TNF-α, TNF-alpha, TNF-a, TNFa, Tumor necrosis factor-alpha, TNF, DIF-alpha, TNFA, TNFSF2, TNLG1F
Cell typeT cell, Tc, Th1, Th2, Th17, Tfh, Monocyte/MΦ
Gene ID7124

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