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Jul 7 | Great news for RNA-based cancer vaccines


Very nice data from Sahin et al (Nature, 2017), showing that neo-epitope vaccination works in human subjects with melanoma.

The authors sequenced RNA from tumor biopsies to identify mutations that could serve as HLA-binding neo-epitopes. The resulting RNA-based vaccines were subsequently injected into a lymph node of the patient, and the idea is that dendritic cells will engulf the vaccine, translate the RNA-encoded antigens and present them to T cells.

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Jul 6 | Launch of Bovine IgG ELISpot


With our new Bovine IgG ELISpot kit, you will be able to quantify the number of antibody producing plasma cells from cow. Antibodies are available as separate reagents.

The new kit and antibodies can be found in our webshop.

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"I have compared Mabtech ELISpot assay to ELISpot assays we run at our company on regular basis "head-to-head" using identical samples. Mabtech's kits proved to be superior to our protocol, had significantly lower background and provided better and higher detection of spots."
Dr. Weiss
"I cannot compare the new mouse IL-10 system to the old system, as I never used it, but I was able to obtain very nice results with the new system. The spots show up clearly and there is no variation in the background color of the membranes (this is a problem I have had with other companies' kits, and am told it has to do with uneven pre-coating). I have used other Mabtech products in the past (human and mouse IFN-gamma, IL-2, and TNF-alpha) and will continue to use them. I especially like when the kits are available with pre-coated plates, because I when I have to do the pre-coating myself, I can never seem to remove the underdrain without tearing the filters. "
Julie Roda, PhD
NGM Biopharmaceuticals Inc
"Mabtech service is highly customer-friendly and efficient. We have been using Mabtech ELISA kits for the past eight years with full satisfaction. Furthermore, I find Mabtech products the best for even developing my in-house ELISA."
Laksiri Gomes
Centre for Dengue Research
University of Sri Jayawardenepura