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NEWS

Sep 28 | A new apoD citation in our data base


Herzig et al. have analyzed plasma apoD with our ELISA. The authors have made an interesting study showing that physical activity per se and not loss in body weight attenuated several circulating lipoprotein lipids in sedentary overweight subjects. This means that physical activity already at a low activity level could have long term prevention effects on cardio-metabolic diseases.

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Sep 26 | Live cells after FluoroSpot assay enable plasticity studies


Abhishek Das and colleagues take advantage of the (underappreciated) fact that cells are alive and well after a FluoroSpot assay. By a clever single-cell sorting procedure of T cells onto an IFN-gamma/IL-8 FluoroSpot plate, the authors were able to first confirm that recent thymic emigrants produce only IL-8 and not IFN-gamma, and then – by removing the still alive cells with a pipette and transferring them to another plate for cloning – show that the very same cells transitioned into IFN-gamma producing Th1 cells.

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"I cannot compare the new mouse IL-10 system to the old system, as I never used it, but I was able to obtain very nice results with the new system. The spots show up clearly and there is no variation in the background color of the membranes (this is a problem I have had with other companies' kits, and am told it has to do with uneven pre-coating). I have used other Mabtech products in the past (human and mouse IFN-gamma, IL-2, and TNF-alpha) and will continue to use them. "
Julie Roda, PhD
NGM Biopharmaceuticals Inc
USA
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Marie de Bourayne
France
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Michelle Somerville
Cardiff University
United Kingdom