Anti-human Granzyme B mAb (MT8610), biotin

Anti-human Granzyme B mAb (MT8610), biotin

3486-6-250

Publications: 62
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Intended use

This monoclonal antibody enables specific detection of human Granzyme B in ELISpot.

Serum/Plasma samples

Recommendation

MT8610 is recommended as detection mAb in ELISpot in combination with capture mAb MT28 (product code 3486-3).

Product details

ProductAnti-human Granzyme B mAb (MT8610), biotin
ApplicationELISpot
AnalyteGranzyme B
AntibodyMT8610
ConjugateBiotin
ClonalityMonoclonal
ImmunogenRecombinant human Granzyme B
HostMouse
IsotypeIgG1
ReactivityHuman
Specificity

Native and recombinant human Granzyme B

Purification

Purified from in vitro cultures by protein G affinity chromatography.

Biotinylation

Biotinylated through reaction with a N-hydroxysuccinimide ester of biotin.

Concentration0.5 mg/ml
Supplied in

PBS with 0.02% sodium azide. Sterile-filtered (0.2 µm).

Contents

Monoclonal antibody MT8610, biotinylated. Supplied at 0.5 mg/ml in PBS with 0.02% sodium azide.

Shipping and Storage

Shipping

Shipped at ambient temperature.

Storage

Store product at 4-8°C or frozen at -20°C or below. Avoid repeated freezing/thawing.

Shelf lifeAt least 18 months from date of receipt.

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Granzyme B

Analyte description

Granzyme B is a serine protease released by the cytoplasmic granules within cytotoxic T cells and NK cells. Granzyme B will act together with perforin and other cytotoxic mediators to induce target cell death by apoptosis.

Alternative namesGranzyme B, GzmB, GrB, GrzB, C11, CCPI, CGL-1, CGL1, CSP-B, CSPB, CTLA1, CTSGL1, HLP, SECT
Cell typeT cell, Tc, Th1, NK cell
Gene ID3002

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