Catalog / apoE antibodies
apoE antibodies
We make 5 apoE antibodies for 3 species, unconjugated or conjugated to biotin. This page explains how they differ, so you can pick the one your experiment needs.
Rather use a ready-made kit? See our apoE ELISA kits.
What differs between these antibodies
Which species they are for
Available for Human, Mouse, and Human/monkey. The species decides which clones there are, so it is the first thing to choose. Many also cross-react with related species, so if you work in one we do not list here, check the reactivity on the product page.
Which clone
We make 5 apoE antibody clones. A clone is one specific antibody that binds one site on its target, so it is what you cite or reorder by name. A sandwich assay needs two clones that bind different sites; the capture and detection pairs below are matched for that.
Which conjugate
Unconjugated antibodies carry no label. You coat a plate with them as the capture antibody, or use them where the antibody itself is the reagent. Biotinylated antibodies are detected with a streptavidin conjugate, such as streptavidin-ALP or streptavidin-HRP.
Capture and detection pairs
To build your own apoE ELISA or ELISpot, coat with the unconjugated capture antibody and detect with the biotinylated detection antibody, then a streptavidin conjugate. These are the same pairs our own kits use.
| Species | Capture | Detection | For |
|---|---|---|---|
| HumanELISA, ELISpot | E276 | E887, biotin | ELISA, ELISpot |
| MouseELISA | mE1 | mE29, biotin | ELISA |
About apoE
Apolipoprotein E (apoE) is a 34 kD glycoprotein involved in lipid transport, lipoprotein metabolism, and cellular signaling. It is present in plasma lipoprotein particles such as chylomicrons, VLDL, and HDL. ApoE is also present in large amounts at sites of neurological damage and appears to be involved in the recycling of apoptotic remnants and amyloidal aggregates. ApoE is mainly produced in the liver and by macrophages, but also by other cell types such as smooth muscle cells or neuronal cells. In humans, apoE exists in three isoforms, apoE2, apoE3, and apoE4. Of these, apoE4 is associated with Alzheimer’s disease. A normal concentration of apoE in human plasma is approximately 30-40 µg/ml. The concentration of ApoE in inbred mouse plasma can vary between 15-150 µg/ml.
Find the right apoE antibody
Choose what your experiment needs. When your choices match a single antibody, we'll link you to its product page for prices and ordering.
Species
What you are measuring in
Application
What you will use it for
Conjugate
Unlabelled or labelled
Clone
If you already know which
Start by choosing a species.
Related reading
Guides and tutorials covering apoE and how to use these antibodies.
