ELISA Flex: Porcine IL-17A (HRP)
ELISA Flex: Porcine IL-17A (HRP)
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An ELISA designed to detect the native protein – in our most adaptable kit format to match your unique setup. Combine it with your preferred substrate and buffer.
Components
| Capture mAb | MT49A7 |
| Detection mAb | MTP853, biotin |
| Enzyme conjugate | Streptavidin-HRP |
| Standard | Recombinant bovine IL-17A ELISA standard |
| Buffer/Solution | Standard reconstitution buffer |
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Performance
| Standard range | 10-1000 pg/ml |
Representative standard curve for porcine IL-17A ELISA Flex kit using TMB substrate.
Documents
Veterinary cross-reactivity guide
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Analyte information
IL-17A
| Analyte description | Interleukin 17A (IL-17A) is a potent proinflammatory cytokine produced by activated Th17 (T helper 17) cells and certain cells belonging to the innate immune system. In mice, IL-17 has also been shown to be produced by activated CD8 T cells and γδ T cells. Th17 cells play an important role in autoimmune diseases and protection against bacteria and fungi. IL-17A acts on a broad range of cell types to induce the expression of cytokines, chemokines, and metalloproteinases. As a result, secretion of IL-17A promotes inflammatory responses, which leads to the recruitment of neutrophils, enhancement of antibody production, and activation of T cells. Increased expression of IL-17A is seen in autoimmune diseases such as multiple sclerosis and rheumatoid arthritis. It is also associated with asthma, psoriasis, cancer, and transplant rejection. |
| Alternative names | Interleukin 17A, IL-17A, IL17A, IL17 |
| Cell type | Th17 |
| Gene ID | 449530 |