Anti-mouse IL-4 mAb (11B11), azide free

Anti-mouse IL-4 mAb (11B11), azide free

3311-3N-500

Publications: 3
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Content

Monoclonal antibody 11B11, unconjugated. Supplied at 1 mg/ml in PBS, free of preservatives.

In stock

Delivery 4-9 business days

Shipping $0

Product specifications

Intended use

This monoclonal antibody enables neutralization of mouse IL-4 bioactivity.

Serum/Plasma samples

Recommendation

It is recommended to establish the optimal antibody concentration for the assay system used.

Product details

ProductAnti-mouse IL-4 mAb (11B11), azide free
ApplicationNeutralization
AnalyteIL-4
Antibody11B11
ConjugateUnconjugated
ClonalityMonoclonal
ImmunogenRecombinant mouse IL-4
HostRat
IsotypeIgG1
ReactivityMouse
Specificity

Native and recombinant mouse IL-4

Purification

Purified from in vitro cultures by protein G affinity chromatography.

Concentration1 mg/ml
Supplied in

PBS with 0.02% sodium azide. Sterile-filtered (0.2 µm).

Contents

Monoclonal antibody 11B11, unconjugated. Supplied at 1 mg/ml in PBS, free of preservatives.

Shipping and Storage

Shipping

Shipped at ambient temperature.

Storage

Store product at 4-8°C or frozen at -20°C or below. Avoid repeated freezing/thawing.

Shelf lifeAt least 12 months from date of receipt.
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IL-4

Analyte description

Interleukin 4 (IL-4) is produced primarily by Th2 cells, mast cells, eosinophils, and basophils. IL-4 was first identified to costimulate B cell growth; the cytokine is essential for B cell secretion of IgE and augments the production of IgG1 in vivo. In addition to regulating B cell growth and immunoglobulin secretion, IL-4 also affects T cells. In vitro, IL-4 promotes T cell growth and can induce cytolytic T cell activity. IL-4 also induces the differentiation of naive CD4 T cells into Th2 cells, which are characterized by their capacity to secrete the cytokines IL-4, IL-5, and IL-10 upon activation, while simultaneously inhibiting the generation of Th1 cells.

Alternative namesInterleukin 4, IL-4, IL4, BCGF-1, BSF-1, Il-4
Cell typeT cell, Th2, Treg
Gene ID16189
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