Anti-human CCL2 mAb (capture), unconjugated
Anti-human CCL2 mAb (capture), unconjugated
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CCL2 (MCP-1)
| Analyte description | Chemokine ligand 2 (CCL2), also called monocyte chemoattractant protein-1 (MCP-1) and JE, belongs to the CC chemokine family. CCL2 is secreted by a wide array of cells including monocytes, macrophages, dendritic cells, endothelial cells, astrocytes, and osteoblasts. In addition to its chemotactic properties, CCL2 is involved in processes of degranulation, upregulation of receptors, cell survival, and secretion of cytokines. Its presence in multiple tissues has been linked to various diseases such as Alzheimer's, diabetes, tuberculosis, osteoporosis, and cancer where CCL2 plays a role in tumor microenvironment. |
| Alternative names | C-C motif chemokine 2, Chemoattractant Protein 1, MCP-1, MCP1, HC11, GDCF-2, HSMCR30, MCAF, SCYA2, SMC-CF |
| Cell type | Monocyte/MΦ |
| Gene ID | 6347 |
