Anti-human CCL2 mAb (detection), biotin

Standard curve for human CCL2 in bead-based multiplex.

Anti-human CCL2 mAb (detection), biotin

5311-6-100

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Anti-human CCL2 mAb (capture), unconjugated

Intended use

This monoclonal antibody enables specific detection of human CCL2 in bead-based multiplex assays. For research use only. Not for use in diagnostic procedures.

Serum/Plasma samples

Recommendation

Anti-human CCL2 mAb (detection) is recommended in combination with Anti-human CCL2 mAb (capture) (product code 5311-3) in bead-based multiplex.

Product details

Product	Anti-human CCL2 mAb (detection), biotin
Application	Bead-based multiplex
Analyte	CCL2 (MCP-1)
Antibody	Anti-human CCL2 mAb (detection)
Conjugate	Biotin
Clonality	Monoclonal
Reactivity	Human
Specificity	Native and recombinant human CCL2
Purification	Purified from in vitro cultures by protein G affinity chromatography.
Biotinylation	Biotinylated through reaction with a N-hydroxysuccinimide ester of biotin.
Concentration	0.5 mg/ml
Supplied in	PBS with 0.02% sodium azide. Sterile-filtered (0.2 µm).
Contents	Anti-human CCL2 mAb (detection), biotin. Supplied at 0.5 mg/ml in PBS with 0.02% sodium azide.

Shipping and Storage

Shipping	Shipped at ambient temperature.
Storage	Store product at 4-8°C.
Shelf life	At least 12 months from date of receipt.

Representative standard curve for human CCL2 in bead-based multiplex.

Datasheet/Protocol SDS

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CCL2 (MCP-1)

Analyte description	Chemokine ligand 2 (CCL2), also called monocyte chemoattractant protein-1 (MCP-1) and JE, belongs to the CC chemokine family. CCL2 is secreted by a wide array of cells including monocytes, macrophages, dendritic cells, endothelial cells, astrocytes, and osteoblasts. In addition to its chemotactic properties, CCL2 is involved in processes of degranulation, upregulation of receptors, cell survival, and secretion of cytokines. Its presence in multiple tissues has been linked to various diseases such as Alzheimer's, diabetes, tuberculosis, osteoporosis, and cancer where CCL2 plays a role in tumor microenvironment.
Alternative names	C-C motif chemokine 2, Chemoattractant Protein 1, MCP-1, MCP1, HC11, GDCF-2, HSMCR30, MCAF, SCYA2, SMC-CF
Cell type	Monocyte/MΦ
Gene ID	6347