Catalog / IL-4 antibodies
IL-4 antibodies
We make 9 IL-4 antibodies for 3 species, unconjugated or conjugated to biotin. This page explains how they differ, so you can pick the one your experiment needs.
Rather use a ready-made kit? See our IL-4 ELISA kits and IL-4 ELISpot kits.
What differs between these antibodies
Which species they are for
Available for Human, Mouse, and Bovine. The species decides which clones there are, so it is the first thing to choose. Many also cross-react with related species, so if you work in one we do not list here, check the reactivity on the product page.
Which clone
We make 8 IL-4 antibody clones. A clone is one specific antibody that binds one site on its target, so it is what you cite or reorder by name. A sandwich assay needs two clones that bind different sites; the capture and detection pairs below are matched for that.
Which conjugate
Unconjugated antibodies carry no label. You coat a plate with them as the capture antibody, or use them where the antibody itself is the reagent, such as for neutralization. Biotinylated antibodies are detected with a streptavidin conjugate, such as streptavidin-ALP or streptavidin-HRP.
Which formulation
Some come azide-free. Sodium azide preserves the standard formulation but is toxic to cells, so choose the azide-free version for work with live cells.
Capture and detection pairs
To build your own IL-4 ELISA or ELISpot, coat with the unconjugated capture antibody and detect with the biotinylated detection antibody, then a streptavidin conjugate. These are the same pairs our own kits use.
| Species | Capture | Detection | For |
|---|---|---|---|
| HumanELISA, ELISpot | IL4-I | IL4-II, biotin | ELISA, ELISpot |
| BovineELISA, ELISpot | bIL4-I | bIL4-II, biotin | ELISA, ELISpot |
About IL-4
Interleukin 4 (IL-4) is produced primarily by Th2 cells, mast cells, eosinophils, and basophils. IL-4 was first identified to costimulate B cell growth; the cytokine is essential for B cell secretion of IgE and augments the production of IgG1 in vivo. In addition to regulating B cell growth and immunoglobulin secretion, IL-4 also affects T cells. In vitro, IL-4 promotes T cell growth and can induce cytolytic T cell activity. IL-4 also induces the differentiation of naive CD4 T cells into Th2 cells, which are characterized by their capacity to secrete the cytokines IL-4, IL-5, and IL-10 upon activation, while simultaneously inhibiting the generation of Th1 cells.
Find the right IL-4 antibody
Choose what your experiment needs. When your choices match a single antibody, we'll link you to its product page for prices and ordering.
Species
What you are measuring in
Application
What you will use it for
Conjugate
Unlabelled or labelled
Formulation
Preservative and concentration
Clone
If you already know which
Start by choosing a species.