Delivery 4-9 business days
Intended useThese monoclonal antibodies enable specific detection of mouse IFN-α in ELISpot.
RecommendationMT9L/24A/44A are recommended as detection mAbs in ELISpot in combination with capture mAbs MT14A/104/113 (product code 3326-3).
|Product||Anti-mouse IFN-α mAbs (MT9L/24A/44A), biotin|
|Immunogen||Recombinant mouse IFN-α|
|Specificity||Native and recombinant mouse IFN-α. MT9L/24A/44A in combination with antibodies MT14A/104/113 detect subtypes 1, 2, 4, 5, 6T, 7/10 (129/Sv), 8/6, 9, 11, 12, 13, 14, 15 (A), and B.|
|Purification||Purified from in vitro cultures by protein G affinity chromatography.|
|Biotinylation||Biotinylated through reaction with a N-hydroxysuccinimide ester of biotin.|
|Supplied in||PBS with 0.02% sodium azide. Sterile-filtered (0.2 µm).|
|Contents||Monoclonal antibodies MT9L/24A/44A, biotinylated. Supplied at 0.5 mg/ml in PBS with 0.02% sodium azide.|
Shipping and Storage
|Shipping||Shipped at ambient temperature.|
|Storage||Store product at 4-8°C or frozen at -20°C or below. Avoid repeated freezing/thawing.|
|Shelf life||At least 18 months from date of receipt.|
Interferon-α and interferon-β are type I interferons. These antiviral cytokines are mainly produced by virus-infected cells after sensing the presence of danger signals such as viral DNA or RNA. IFN-α and IFN-β act through the same receptor and initiate an anti-viral response, affect immune regulation, T cell responses, and also anti-tumor effects have been shown. A key producer of type I interferons is the plasmacytoid dendritic cell. Additionally, IFN-α is secreted by lymphocytes, macrophages, fibroblasts, and dendritic cells.
|Alternative names||Interferon-α, Interferon-alpha, IFN-α, IFN-alpha, IFN-a, IFNA|