Anti-human/monkey Granzyme B mAb (MT8213), biotin

3486M-6-250

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Anti-monkey Granzyme B mAb (MTAG8), unconjugated

Intended use

This monoclonal antibody enables specific detection of monkey granzyme B in immunoassays such as ELISpot, FluoroSpot, and ELISA.

Serum/Plasma samples

Recommendation

MT8213 is recommended as detection mAb in ELISpot, FluoroSpot, and ELISA in combination with capture mAb MTAG8 (product code 3486M-3).

Product details

Product	Anti-human/monkey Granzyme B mAb (MT8213), biotin
Application	ELISpot, FluoroSpot, ELISA
Analyte	Granzyme B
Antibody	MT8213
Conjugate	Biotin
Clonality	Monoclonal
Immunogen	Recombinant human granzyme B
Host	Mouse
Isotype	IgG1
Reactivity	Non-human primates, Human
Specificity	Native and recombiant granzyme B from rhesus and cynomolgus macaques. Native and recombinant human granzyme B.
Cross-reactivity	For information on reactivity with other non-human primates (NHP), please check the NHP cross-reactivity guide.
Purification	Purified from in vitro cultures by protein G affinity chromatography.
Biotinylation	Biotinylated through reaction with a N-hydroxysuccinimide ester of biotin.
Concentration	0.5 mg/ml
Supplied in	PBS with 0.02% sodium azide. Sterile-filtered (0.2 µm).
Contents	Monoclonal antibody MT8213, biotinylated. Supplied at 0.5 mg/ml in PBS with 0.02% sodium azide.

Shipping and Storage

Shipping	Shipped at ambient temperature.
Storage	Store product at 4-8°C or frozen at -20°C or below. Avoid repeated freezing/thawing.
Shelf life	At least 18 months from date of receipt.

New positive control peptide pools: CEFRAS Global

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Granzyme B

Analyte description	Granzyme B is a serine protease released by the cytoplasmic granules within cytotoxic T cells and NK cells. Granzyme B will act together with perforin and other cytotoxic mediators to induce target cell death by apoptosis.
Alternative names	Granzyme B, GzmB, GrB, GrzB
Cell type	T cell, Tc, Th1, NK cell
Gene ID	716518