Anti-human IL-22 mAb (detection), biotin

Standard curve for human IL-22 in bead-based multiplex.

Anti-human IL-22 mAb (detection), biotin

5331-6-100

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Intended use

This monoclonal antibody enables specific detection of human IL-22 in bead-based multiplex assays. For research use only. Not for use in diagnostic procedures.

Serum/Plasma samples

Recommendation

Anti-human IL-22 mAb (detection) is recommended in combination with Anti-human IL-22 mAb (capture) (product code 5331-3) in bead-based multiplex.

Product details

ProductAnti-human IL-22 mAb (detection), biotin
ApplicationBead-based multiplex
AnalyteIL-22
AntibodyAnti-human IL-22 mAb (detection)
ConjugateBiotin
ClonalityMonoclonal
ReactivityHuman
Specificity

Native and recombinant human IL-22

Purification

Purified from in vitro cultures by protein G affinity chromatography.

Biotinylation

Biotinylated through reaction with a N-hydroxysuccinimide ester of biotin.

Concentration0.5 mg/ml
Supplied in

PBS with 0.02% sodium azide. Sterile-filtered (0.2 µm).

Contents

Anti-human IL-22 mAb (detection), biotin. Supplied at 0.5 mg/ml in PBS with 0.02% sodium azide.

Shipping and Storage

Shipping

Shipped at ambient temperature.

Storage

Store product at 4-8°C.

Shelf lifeAt least 12 months from date of receipt.

Standard curve for human IL-22 in bead-based multiplex.

Representative standard curve for human IL-22 in bead-based multiplex.

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IL-22

Analyte description

The cytokine interleukin 22 (IL-22) is mainly produced by activated CD4 T helper 17 (Th17) and T helper 22 (Th22) cells. The IL-22 receptor is expressed on non-immune cells, particularly epithelial cells and keratinocytes, and IL-22 promotes innate immune responses versus bacterial infections in these target cells. In addition, Th22 cells have been shown to play a role in the pathophysiology of several human skin diseases.

Alternative namesInterleukin-22, IL-22, IL22, IL-21, IL-D110, IL-TIF, ILTIF, TIFIL-23, TIFa, zcyto18
Cell typeT cell, Th1, Th17, Tfh
Gene ID50616