Anti-human IL-22 mAb (MT7B27), biotin

3475-6-250

Publications: 22

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Anti-human IL-22 mAb (MT12A3), unconjugated

Intended use

This monoclonal antibody enables specific detection of human IL-22 in immunoassays such as ELISpot, FluoroSpot, and ELISA.

Serum/Plasma samples

Recommendation

MT7B27 is recommended as detection mAb in ELISpot, FluoroSpot, and ELISA in combination with capture mAb MT12A3 (product code 3475-3).

Product details

Product	Anti-human IL-22 mAb (MT7B27), biotin
Application	ELISpot, FluoroSpot, ELISA
Analyte	IL-22
Antibody	MT7B27
Conjugate	Biotin
Clonality	Monoclonal
Immunogen	Recombinant human IL-22
Host	Rat
Isotype	IgG2a
Reactivity	Human
Specificity	Native and recombinant human IL-22
Purification	Purified from in vitro cultures by protein G affinity chromatography.
Biotinylation	Biotinylated through reaction with a N-hydroxysuccinimide ester of biotin.
Concentration	0.5 mg/ml
Supplied in	PBS with 0.02% sodium azide. Sterile-filtered (0.2 µm).
Contents	Monoclonal antibody MT7B27, biotinylated. Supplied at 0.5 mg/ml in PBS with 0.02% sodium azide.

Shipping and Storage

Shipping	Shipped at ambient temperature.
Storage	Store product at 4-8°C or frozen at -20°C or below. Avoid repeated freezing/thawing.
Shelf life	At least 18 months from date of receipt.

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IL-22

Analyte description	The cytokine interleukin 22 (IL-22) is mainly produced by activated CD4 T helper 17 (Th17) and T helper 22 (Th22) cells. The IL-22 receptor is expressed on non-immune cells, particularly epithelial cells and keratinocytes, and IL-22 promotes innate immune responses versus bacterial infections in these target cells. In addition, Th22 cells have been shown to play a role in the pathophysiology of several human skin diseases.
Alternative names	Interleukin-22, IL-22, IL22, IL-21, IL-D110, IL-TIF, ILTIF, TIFIL-23, TIFa, zcyto18
Cell type	T cell, Th1, Th17, Tfh
Gene ID	50616

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ELISpot Plus: Human IL-22 (ALP)