Anti-human IL-12 (p70) mAb (detection), biotin

Standard curve for human IL-12 (p70) in bead-based multiplex.

Anti-human IL-12 (p70) mAb (detection), biotin

5327-6-100

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Anti-human IL-12/-23 (p40) mAb (capture), unconjugated

Intended use

This monoclonal antibody enables specific detection of human IL-12 (p70) in bead-based multiplex assays. For research use only. Not for use in diagnostic procedures.

Serum/Plasma samples

Recommendation

Anti-human IL-12 (p70) mAb (detection) is recommended in combination with Anti-human IL-12/-23 (p40) mAb (capture) (product code 5327-3) for detection of human IL-12 (p70) in bead-based multiplex.

Product details

Product	Anti-human IL-12 (p70) mAb (detection), biotin
Application	Bead-based multiplex
Analyte	IL-12 (p70)
Antibody	Anti-human IL-12 (p70) mAb (detection)
Conjugate	Biotin
Clonality	Monoclonal
Reactivity	Human
Specificity	Native and recombinant human IL-12 (p70)
Purification	Purified from in vitro cultures by protein G affinity chromatography.
Biotinylation	Biotinylated through reaction with a N-hydroxysuccinimide ester of biotin.
Concentration	0.5 mg/ml
Supplied in	PBS with 0.02% sodium azide. Sterile-filtered (0.2 µm).
Contents	Anti-human IL-12 (p70) mAb (detection), biotin. Supplied at 0.5 mg/ml in PBS with 0.02% sodium azide.

Shipping and Storage

Shipping	Shipped at ambient temperature.
Storage	Store product at 4-8°C.
Shelf life	At least 12 months from date of receipt.

Representative standard curve for human IL-12 (p70) in bead-based multiplex.

Datasheet/Protocol SDS

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IL-12 (p70)

Analyte description	Interleukin 12 (IL-12) is, when biologically active, a heterodimer (p70) consisting of two covalently linked subunits, p35 and p40. The p40 subunit is shared with IL-23. IL-12 is produced by antigen-presenting cells, specifically dendritic cells, and macrophages. IL-12 is a proinflammatory cytokine that promotes Th1-type responses by inducing IFN-γ production and enhancing the proliferation and cytotoxicity of NK and T cells.
Alternative names	Interleukin 12, IL-12, IL12, CLMF, IL-12A, NFSK, NKSF1, P35, CLMF2, IL-12B, IMD28, IMD29, NKSF, NKSF2
Cell type	Monocyte/MΦ, mDC
Gene ID	3592, 3593