Delivery 4-9 business days
Intended useThis monoclonal antibody enables specific detection of human IFN-α (subtype 2) in immunoassays such as ELISpot and ELISA.
RecommendationMT1 is recommended as capture mAb in ELISpot and ELISA in combination with detection mAb MT2 (product code 3423-6).
|Product||Anti-human IFN-α mAb (MT1), unconjugated|
|Immunogen||Recombinant human IFN-α 2c|
|Specificity||Native and recombinant human IFN-α subtypes 2a, 2b and 2c|
|Purification||Purified from in vitro cultures by protein G affinity chromatography.|
|Supplied in||PBS with 0.02% sodium azide. Sterile-filtered (0.2 µm).|
|Contents||Monoclonal antibody MT1, unconjugated. Supplied at 1 mg/ml in PBS with 0.02% sodium azide.|
Shipping and Storage
|Shipping||Shipped at ambient temperature.|
|Storage||Store product at 4-8°C or frozen at -20°C or below. Avoid repeated freezing/thawing.|
|Shelf life||At least 18 months from date of receipt.|
Interferon-α (IFN-α) is a type I interferon. In humans, there are 13 IFN-α subtypes: IFN-α 1, 2, 4, 5, 6, 7, 8, 10, 13, 14, 16, 17, and 21. Like the other subtypes, interferon-α2 is mainly produced by virus-infected cells after sensing the presence of danger signals such as viral DNA or RNA. The binding of IFN-α2 to its receptor thus initiates an anti-viral response, but also anti-tumor effects have been shown. Being the first to be discovered, IFN-α2 is the most widely studied subtype. It has been used as a cytokine therapy versus hepatitis C virus infections.
|Alternative names||Interferon-α2, Interferon-alpha2, IFN-α2, IFN-alpha2, IFN-a2, IFNA2, IFN-alpha-2, IFN-alphaA, IFNAB, leIF A|