What is CXCL1 (KC/GRO-α)?
CXCL1, also known as KC/GRO-α, is an ELR-positive chemokine secreted by macrophages, neutrophils, epithelial cells, and endothelial cells. Signaling through the receptor CXCR2, its main role is to drive the rapid recruitment of neutrophils to sites of infection and tissue damage. CXCL1 is a key mediator of the earliest phase of the innate immune response, making it a valuable marker for researchers studying acute inflammation and host defense.
| Alternative analyte names: | GRO, GRO1, GROA, MGSA, SCYB1, CXCL1, Growth-regulated alpha protein, C-X-C motif chemokine 1, GRO-alpha(1-73), Melanoma growth stimulatory activity, Neutrophil-activating protein 3, NAP-3 |
| Cell types: | Monocyte/MΦ |
| Products: | Click here to see our portfolio of CXCL1 (KC/GRO-α) products. |