Catalog / IL-31 antibodies
IL-31 antibodies
We make 3 IL-31 antibodies for human, unconjugated or conjugated to biotin. This page explains how they differ, so you can pick the one your experiment needs.
Rather use a ready-made kit? See our IL-31 ELISA kits and IL-31 ELISpot kits.
What differs between these antibodies
Which clone
We make 3 IL-31 antibody clones. A clone is one specific antibody that binds one site on its target, so it is what you cite or reorder by name. A sandwich assay needs two clones that bind different sites; the capture and detection pairs below are matched for that.
Which conjugate
Unconjugated antibodies carry no label. You coat a plate with them as the capture antibody, or use them where the antibody itself is the reagent, such as for neutralization. Biotinylated antibodies are detected with a streptavidin conjugate, such as streptavidin-ALP or streptavidin-HRP.
Which formulation
Some come azide-free. Sodium azide preserves the standard formulation but is toxic to cells, so choose the azide-free version for work with live cells.
Capture and detection pairs
To build your own IL-31 ELISA or ELISpot, coat with the unconjugated capture antibody and detect with the biotinylated detection antibody, then a streptavidin conjugate. These are the same pairs our own kits use.
| Species | Capture | Detection | For |
|---|---|---|---|
| HumanELISA, ELISpot | MT31/88 | MT158, biotin | ELISA, ELISpot |
About IL-31
Interleukin 31 (IL-31) is a cytokine belonging to the IL-6 family. It is mainly secreted by activated T cells, especially in Th2 helper cells, mast cells, macrophages, and dendritic cells. IL-31 mainly acts in the skin, lung, intestine, and nervous system, facilitating cell-mediated immunity against pathogens. The receptor for IL-31 is found on e.g. keratinocytes and endothelial cells and can be upregulated on activated monocytes. However, IL-31 is considered a Th2-type cytokine with different functions than other Th2-type cytokines. In transgenic mice overexpressing IL-31, the cytokine induces pruritus and dermatitis resembling human atopic dermatitis (AD). In humans, IL-31 has been associated with AD, atopic and contact allergies, airway hypersensitivity, and inflammatory bowel disease.
| Also known as | Interleukin-31, IL-31, IL31 |
| Produced by | T cell, Tc, Th1, NK cell |
| Species | Human |
| Gene ID | Homo sapiens: 386653 |
Find the right IL-31 antibody
Choose what your experiment needs. When your choices match a single antibody, we'll link you to its product page for prices and ordering.
Application
What you will use it for
Conjugate
Unlabelled or labelled
Formulation
Preservative and concentration
Clone
If you already know which
Next, choose what you will use it for.