Catalog / IL-17A antibodies
IL-17A antibodies
We make 13 IL-17A antibodies for 5 species, unconjugated or conjugated to biotin. This page explains how they differ, so you can pick the one your experiment needs.
Rather use a ready-made kit? See our IL-17A ELISA kits and IL-17A ELISpot kits.
What differs between these antibodies
Which species they are for
Available for Human, Mouse, Bovine, Human/monkey, and Porcine. The species decides which clones there are, so it is the first thing to choose. Many also cross-react with related species, so if you work in one we do not list here, check the reactivity on the product page.
Which clone
We make 11 IL-17A antibody clones. A clone is one specific antibody that binds one site on its target, so it is what you cite or reorder by name. A sandwich assay needs two clones that bind different sites; the capture and detection pairs below are matched for that.
Which conjugate
Unconjugated antibodies carry no label. You coat a plate with them as the capture antibody, or use them where the antibody itself is the reagent, such as for neutralization. Biotinylated antibodies are detected with a streptavidin conjugate, such as streptavidin-ALP or streptavidin-HRP.
Which formulation
Some come azide-free. Sodium azide preserves the standard formulation but is toxic to cells, so choose the azide-free version for work with live cells.
Capture and detection pairs
To build your own IL-17A ELISA or ELISpot, coat with the unconjugated capture antibody and detect with the biotinylated detection antibody, then a streptavidin conjugate. These are the same pairs our own kits use.
| Species | Capture | Detection | For |
|---|---|---|---|
| HumanELISA, ELISpot | MT44.6 | MT504, biotin | ELISA, ELISpot |
| BovineELISA, ELISpot | MT49A7 | MT51B8, biotin | ELISA, ELISpot |
About IL-17A
Interleukin 17A (IL-17A) is a potent proinflammatory cytokine produced by activated Th17 (T helper 17) cells and certain cells belonging to the innate immune system. In mice, IL-17 has also been shown to be produced by activated CD8 T cells and γδ T cells. Th17 cells play an important role in autoimmune diseases and protection against bacteria and fungi. IL-17A acts on a broad range of cell types to induce the expression of cytokines, chemokines, and metalloproteinases. As a result, secretion of IL-17A promotes inflammatory responses, which leads to the recruitment of neutrophils, enhancement of antibody production, and activation of T cells. Increased expression of IL-17A is seen in autoimmune diseases such as multiple sclerosis and rheumatoid arthritis. It is also associated with asthma, psoriasis, cancer, and transplant rejection.
Find the right IL-17A antibody
Choose what your experiment needs. When your choices match a single antibody, we'll link you to its product page for prices and ordering.
Species
What you are measuring in
Application
What you will use it for
Conjugate
Unlabelled or labelled
Formulation
Preservative and concentration
Clone
If you already know which
Start by choosing a species.
Related reading
Guides and tutorials covering IL-17A and how to use these antibodies.
