Catalog / Human IL-31 ELISA kits

Human IL-31 ELISA kits

Pick the right ELISA kit for Human IL-31. Our kits differ in how you develop the signal – this page explains what those differences mean.

What differs between these kits

Which detection system

Available with Streptavidin-ALP or Streptavidin-HRP. You add the streptavidin conjugate as a second incubation after the biotinylated antibody, which amplifies the signal. Alkaline phosphatase (ALP) and horseradish peroxidase (HRP) perform equivalently, so that choice usually comes down to the substrate and reader you already work with.

Supplied without a plate, streptavidin conjugate

Supplied without a plate, streptavidin conjugate

About IL-31

These Human IL-31 ELISA kits target IL31 (Homo sapiens, Gene ID 386653).

Interleukin 31 (IL-31) is a cytokine belonging to the IL-6 family. It is mainly secreted by activated T cells, especially in Th2 helper cells, mast cells, macrophages, and dendritic cells. IL-31 mainly acts in the skin, lung, intestine, and nervous system, facilitating cell-mediated immunity against pathogens. The receptor for IL-31 is found on e.g. keratinocytes and endothelial cells and can be upregulated on activated monocytes. However, IL-31 is considered a Th2-type cytokine with different functions than other Th2-type cytokines. In transgenic mice overexpressing IL-31, the cytokine induces pruritus and dermatitis resembling human atopic dermatitis (AD). In humans, IL-31 has been associated with AD, atopic and contact allergies, airway hypersensitivity, and inflammatory bowel disease. 
 

Also known asInterleukin-31, IL-31, IL31
Produced byT cell, Tc, Th1, NK cell
ReactivityHuman
Gene ID386653

Find the right kit

Choose what your experiment needs. When your choices match a single kit, we'll link you to its product page for prices and ordering.

Kit detection system

Which enzyme conjugate we supply


Choose a detection system to continue.

Frequently bought together

What customers usually order alongside these kits.

ELISA substrate: pNPP for ALP

Substrates

ELISA substrate: pNPP for ALP

Related reading

Guides and tutorials covering Human IL-31 and the ELISA method.

Tutorials

Tutorial

2025-04-08

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