Anti-mouse IL-2 mAb (1A12), unconjugated

3441-3-250

Publications: 138

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Anti-mouse IL-2 mAb (5H4), biotin

Intended use

This monoclonal antibody enables specific detection of mouse IL-2 in immunoassays such as ELISpot, FluoroSpot, and ELISA.

Serum/Plasma samples

Recommendation

1A12 is recommended as capture mAb in ELISpot, FluoroSpot, and ELISA in combination with detection mAb 5H4 (product code 3441-6).

Product details

Product	Anti-mouse IL-2 mAb (1A12), unconjugated
Application	ELISpot, FluoroSpot, ELISA
Analyte	IL-2
Antibody	1A12
Conjugate	Unconjugated
Clonality	Monoclonal
Immunogen	Recombinant mouse IL-2
Host	Rat
Isotype	IgG2a
Reactivity	Mouse
Specificity	Native and recombinant mouse IL-2
Purification	Purified from in vitro cultures by protein G affinity chromatography.
Concentration	1 mg/ml
Supplied in	PBS with 0.02% sodium azide. Sterile-filtered (0.2 µm).
Contents	Monoclonal antibody 1A12, unconjugated. Supplied at 1 mg/ml in PBS with 0.02% sodium azide.

Shipping and Storage

Shipping	Shipped at ambient temperature.
Storage	Store product at 4-8°C or frozen at -20°C or below. Avoid repeated freezing/thawing.
Shelf life	At least 18 months from date of receipt.

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IL-2

Analyte description	Interleukin 2 (IL-2) is predominantly produced by activated T cells. IL-2 promotes the proliferation, differentiation, and survival of antigen-activated T cells and NK cells. After antigen stimulation, the cytokine also promotes the differentiation of T cells into effector and memory T cells. Therefore IL-2 plays an important role in the body's response to infection. IL-2 is also key to tolerance, as it promotes the differentiation of certain immature T cells into regulatory T cells in the thymus, ultimately preventing autoimmune diseases.
Alternative names	Interleukin-2, Interleukin 2, IL-2, IL2, T cell growth factor, Il-2
Cell type	T cell, Th1, Th2, Th17, Tfh
Gene ID	16183

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ELISpot Plus: Mouse IL-2 (ALP)