Anti-mouse IL-4 mAb (BVD6-24G2), biotin

Anti-mouse IL-4 mAb (BVD6-24G2), biotin


Publications: 176
Validated for our assays.


Monoclonal antibody BVD6-24G2, biotinylated. Supplied at 1 mg/ml in PBS with 0.02% sodium azide.

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Anti-mouse IL-4 mAb (11B11), unconjugated
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  • Code: 3311-3-250
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Product specifications

Intended use

This monoclonal antibody enables specific detection of mouse IL-4 in immunoassays such as ELISpot, FluoroSpot, and ELISA.

Serum/Plasma samples


BVD6-24G2 is recommended as detection mAb in ELISpot, FluoroSpot, and ELISA in combination with capture mAb 11B11 (product code 3311-3).

Product details

ProductAnti-mouse IL-4 mAb (BVD6-24G2), biotin
ApplicationELISpot, FluoroSpot, ELISA
ImmunogenRecombinant mouse IL-4
SpecificityNative and recombinant mouse IL-4
PurificationPurified from in vitro cultures by protein G affinity chromatography.
BiotinylationBiotinylated through reaction with a N-hydroxysuccinimide ester of biotin.
Concentration1 mg/ml
Supplied inPBS with 0.02% sodium azide. Sterile-filtered (0.2 µm).
ContentsMonoclonal antibody BVD6-24G2, biotinylated. Supplied at 1 mg/ml in PBS with 0.02% sodium azide.

Shipping and Storage

ShippingShipped at ambient temperature.
StorageStore product at 4-8°C or frozen at -20°C or below. Avoid repeated freezing/thawing.
Shelf lifeAt least 18 months from date of receipt.


Analyte description

Interleukin 4 (IL-4) is produced primarily by Th2 cells, mast cells, eosinophils, and basophils. IL-4 was first identified to costimulate B cell growth; the cytokine is essential for B cell secretion of IgE and augments the production of IgG1 in vivo. In addition to regulating B cell growth and immunoglobulin secretion, IL-4 also affects T cells. In vitro, IL-4 promotes T cell growth and can induce cytolytic T cell activity. IL-4 also induces the differentiation of naive CD4 T cells into Th2 cells, which are characterized by their capacity to secrete the cytokines IL-4, IL-5, and IL-10 upon activation, while simultaneously inhibiting the generation of Th1 cells.

Alternative namesInterleukin 4, IL-4, IL4, BCGF-1, BSF-1, Il-4
Cell typeT cell, Th2, Treg
Gene ID16189
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