Intended use
This peptide pool is intended for use as a positive control in immunoassays such as ELISpot, FluoroSpot, and flow cytometry assays. It induces cytokine secretion from antigen-specific human CD4 T cells. For research use only. Not for use in diagnostic procedures.
Description
The CEFTA peptide pool induces secretion of e.g., IFN-γ, IL-2, IL-5, and IL-13 from human CD4 T cells. It consists of 35 MHC class II-restricted peptides from human CMV, EBV, influenza virus, tetanus toxin, and adenovirus 5. It is designed to stimulate T cells with a broad array of HLA types. The synthetic peptides are >95% pure.
Published HLA types covered by the CEFTA peptide pool:
HLA-DRB1*01, HLA-DRB1*03, HLA-DRB1*04, HLA-DRB1*07, HLA-DRB1*08, HLA-DRB1*11, HLA-DRB1*13, HLA-DRB1*15, HLA-DRB1*16, HLA-DRB1*53, HLA-DPw2, HLA-DPB1*04, HLA-DQw1, HLA-DQw3, HLA-DQB1*06.