Anti-mouse IFN-α mAbs (MT24A/44A/104), unconjugated

Anti-mouse IFN-α mAbs (MT24A/44A/104), unconjugated

3326-1-250

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Content

Monoclonal antibodies MT24A/44A/104, unconjugated. Supplied at 0.5 mg/ml in PBS with 0.02% sodium azide.

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Anti-mouse IFN-α mAbs (MT9L/14A/113), biotin


Product specifications

Intended use

These monoclonal antibodies enable specific detection of mouse IFN-α in ELISA.

Serum/Plasma samples

Recommendation

MT24A/44A/104 are recommended as capture mAbs in ELISA in combination with detection mAbs MT9L/14A/113 (product code 3326-14).

Product details

ProductAnti-mouse IFN-α mAbs (MT24A/44A/104), unconjugated
ApplicationELISA
AnalyteIFN-α pan
AntibodyMT24A/44A/104
ConjugateUnconjugated
ClonalityMonoclonal
ImmunogenRecombinant mouse IFN-α
HostRat
IsotypeIgG1
ReactivityMouse
SpecificityNative and recombinant mouse IFN-α. MT24A/44A/104 in combination with antibodies MT9L/14A/113 detect subtypes 1, 2, 4, 5, 6T, 7/10 (129/Sv), 8/6, 9, 11, 12, 13, 14, 15 (A), and B.
PurificationPurified from in vitro cultures by protein G affinity chromatography.
Concentration0.5 mg/ml
Supplied inPBS with 0.02% sodium azide. Sterile-filtered (0.2 µm).
ContentsMonoclonal antibodies MT24A/44A/104, unconjugated. Supplied at 0.5 mg/ml in PBS with 0.02% sodium azide.

Shipping and Storage

ShippingShipped at ambient temperature.
StorageStore product at 4-8°C or frozen at -20°C or below. Avoid repeated freezing/thawing.
Shelf lifeAt least 18 months from date of receipt.
Datasheet/Protocol
SDS
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IFN-α pan

Analyte description

Interferon-α and interferon-β are type I interferons. These antiviral cytokines are mainly produced by virus-infected cells after sensing the presence of danger signals such as viral DNA or RNA. IFN-α and IFN-β act through the same receptor and initiate an anti-viral response, affect immune regulation, T cell responses, and also anti-tumor effects have been shown. A key producer of type I interferons is the plasmacytoid dendritic cell. Additionally, IFN-α is secreted by lymphocytes, macrophages, fibroblasts, and dendritic cells. 

In humans, interferon-α has 13 subtypes: IFN-α 1, 2, 4, 5, 6, 7, 8, 10, 13, 14, 16, 17, and 21.

In mice, there are 14 IFN-α subtypes: 1, 2, 4, 5, 6T, 7/10, 8/6, 9, 11, 12, 13, 14, 15 (A), and B. There are also different allelic forms of mouse IFN-α subtypes 1, 7/10, 8/6, and 11 in mouse strains 129/Sv and C57BL/6.

Alternative namesInterferon-α, Interferon-alpha, IFN-α, IFN-alpha, IFN-a, IFNA
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ELISA Flex: Mouse IFN-α (HRP)