Anti-mouse IL-2 mAb (1A12), azide free

Anti-mouse IL-2 mAb (1A12), azide free

3441-3N-500

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Content

Monoclonal antibody 1A12, unconjugated. Supplied at 1 mg/ml in PBS, free of preservatives.

In stock

Delivery 4-9 business days

Shipping $0

Product specifications

Intended use

This monoclonal antibody enables neutralization of mouse IL-2 bioactivity.

Serum/Plasma samples

Recommendation

It is recommended to establish the optimal antibody concentration for the assay system used.

Product details

ProductAnti-mouse IL-2 mAb (1A12), azide free
ApplicationNeutralization
AnalyteIL-2
Antibody1A12
ConjugateUnconjugated
ClonalityMonoclonal
ImmunogenRecombinant mouse IL-2
HostRat
IsotypeIgG2a
ReactivityMouse
Specificity

Native and recombinant mouse IL-2

Purification

Purified from in vitro cultures by protein G affinity chromatography.

Concentration1 mg/ml
Supplied in

PBS, free of preservatives. Sterile-filtered (0.2 µm).

Contents

Monoclonal antibody 1A12, unconjugated. Supplied at 1 mg/ml in PBS, free of preservatives.

Shipping and Storage

Shipping

Shipped at ambient temperature.

Storage

Store product at 4-8°C or frozen at -20°C or below. Avoid repeated freezing/thawing.

Shelf lifeAt least 12 months from date of receipt.
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IL-2

Analyte description

Interleukin 2 (IL-2) is predominantly produced by activated T cells. IL-2 promotes the proliferation, differentiation, and survival of antigen-activated T cells and NK cells. After antigen stimulation, the cytokine also promotes the differentiation of T cells into effector and memory T cells. Therefore IL-2 plays an important role in the body's response to infection. IL-2 is also key to tolerance, as it promotes the differentiation of certain immature T cells into regulatory T cells in the thymus, ultimately preventing autoimmune diseases. 

Alternative namesInterleukin-2, Interleukin 2, IL-2, IL2, T cell growth factor, Il-2
Cell typeT cell, Th1, Th2, Th17, Tfh
Gene ID16183