Monoclonal antibody specific for IFN-γ
This monoclonal antibody is recommended for neutralization of human IFN-γ bioactivity.
The monoclonal antibody is supplied in PBS without preservatives. Endotoxin content is below 10 EU/mg.
Please view the publication by Zuber B. et.al. for more information.
The antibody cross-reacts with IFN-γ from certain non-human primates. Cross-reactivity has been tested in ELISA and/or ELISpot. See the Human/NHP cross-reactivity table.
Upon request, Mabtech's antibodies are available in unconjugated format and may be purchased in bulk. Please contact Mabtech directly for further details.
Interferon-γ (IFN-γ, also known as IFN-gamma, IFN-g, IFNg and Interferon-gamma) is produced mainly by activated T cells and NK cells. It is a proinflammatory cytokine that activates macrophages and endothelial cells, but it also regulates immune responses by effecting APC and T and B cells. Production of IFN-γ by helper T cells as well as cytotoxic T cells is a hallmark of the TH1-type phenotype, thus, high-level production of IFN-γ is typically associated with effective host defense against intracellular pathogens.