The cytokine interleukin 22 (IL-22) is mainly produced by activated CD4 T helper 17 (Th17) and T helper 22 (Th22) cells. The IL-22 receptor is expressed on non-immune cells, particularly epithelial cells and keratinocytes, and IL-22 promotes innate immune responses versus bacterial infections in these target cells. In addition, Th22 cells have been shown to play a role in the pathophysiology of several human skin diseases.
| Alternative analyte names: | Interleukin-22, IL-22, IL22 |
| Cell types: | T cell, Th1, Tfh, Th17 |
| Products: | Click here to see our portfolio of IL-22 products. |