What is IgA1?

IgA1 (Immunoglobulin A1) is one of the two existing IgA isotypes. The proportions of IgA1 and IgA2 secreting B cells differs in various body tissues. Although IgA1 is the most common IgA subclass in serum, IgA represents only 10-15% of the total serum Ig molecules. The IgA found in secretions (secretory IgA or sIgA) is commonly a dimer with two IgA molecules joined by the J chain. Secretory IgA is the most important Ig isotype in mucous surfaces, the area of entry for most pathogens.

Alternative analyte names:Immunoglobulin A1, IgA1
Cell types:B cell
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