Monoclonal antibodies specific for IgE
These monoclonal antibodies are recommended for detection of antigen-specific IgE in e.g. indirect ELISA
More information about Mabtech's IgE antibodies: see Additional info.
Human IgE mAb Guide
Mabtech supplies monoclonal antibodies specific for human IgE. We have optimized combinations of monoclonal antibodies for use in immunoassays such as ELISA and ELISpot.
- Chowdhury P. S., et al. Targeting the junction of CvarepsilonmX and varepsilon-migis for the specific depletion of mIgE-expressing B cells Mol Immunol 52 279, 2012
- Scanlon K. M., et al. IL-17A induces CCL28, supporting the chemotaxis of IgE-secreting B cells Int Arch Allergy Immunol 156 51, 2011
- Wakamatsu T. H., et al. IgE and eosinophil cationic protein (ECP) as markers of severity in the diagnosis of atopic keratoconjunctivitis Br J Ophthalmol 96 581, 2012
The main normal function of IgE (Immunoglobulin E) is believed to be in the protection against parasitic infestation. However, IgE is also associated with allergy and allergen-specific IgE antibodies may trigger allergic reactions in the presence of the proper allergen. IgE is normally found in low amounts in serum/plasma but is significantly increased in allergic individuals and the detection of allergen-specific IgE serves as the basis for many in vitro assays for specific diagnosis of allergy.