Human MIP-1ß (macrophage inflammatory protein-1ß) is produced by activated monocytes/macrophages and by CD8+ T cells in response to antigenic stimuli. Based on its secretion by activated T cells it can serve as an important complement to e.g. IFN-γ and Perforin when analyzing specific, cytotoxic immune responses.
Cross-reactivity has been assessed and confirmed with certain non-human primate species. Please consult this comprehensive table for information about cross-reactivities with non-human primates.
