Anti-Human/Monkey IL-17A mAb MT241; purified
Interleukin-17A (IL-17A) is a potent proinflammatory cytokine produced by activated Th17 (T-helper 17) cells and certain cells belonging to the innate immune system. Th17 cells play an important role in autoimmune diseases and protection against bacteria and fungi. IL-17A acts on a broad range of cell types to induce expression of cytokines, chemokines and metalloproteinases. As a result, secretion of IL-17A promotes inflammatory responses, which leads to the recruitment of neutrophils, enhancement of antibody production and activation of T cells. Increased expression of IL-17A is seen in autoimmune diseases such as multiple sclerosis and rheumatoid arthritis. It is also associated with asthma, psoriasis, cancer and transplant rejection.
Cross-reactivity has been assessed and confirmed with Rhesus and Cynomolgus macaques.
For cross-reactivity with other NHP species, please consult this comprehensive table.
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| Monoclonal antibodies to Human/Monkey IL-17A |
| Code |
Description |
Quantity |
Price |
|
| 3520M-3-1000 |
Anti-Human/Monkey IL-17A mAb MT241; purified |
1 mg |
5 200 SEK
|
| Format: | Purified. Supplied at 0.5 mg/ml. | | Application: | ELISpot (capture), ELISA (capture) | | Reactivity: | Reacts with Human, cross-reacts with Rhesus and Cynomolgus macaques. Please consult this comprehensive table for reactivities with other non-human primates. |
Mouse monoclonal antibody to monkey and human Interleukin-17A, clone MT241. Suitable as capture antibody in ELISA and ELISpot (in combination with clone MT504 biotinylated, code 3520-6).
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