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Mabtech Webshop > Monoclonal Antibodies > Monkey > Interferon-γ
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Interferon-γ
IFN-γ (Interferon-gamma) is produced mainly by activated T cells and NK cells. It is a proinflammatory cytokine that activates macrophages and endothelial cells, but it also regulates immune responses by effecting APC and T and B cells. Production of IFN-γ (Interferon-gamma) by helper T cells as well as cytotoxic T cells is a hallmark of the TH1-type phenotype, thus, high-level production of IFN-γ (Interferon-gamma) is typically associated with effective host defense against intracellular pathogens.
Cross-reactivity has been assessed and confirmed with Rhesus and Cynomolgus macaques.
For cross-reactivity with other NHP species, please consult this comprehensive table.
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