Anti-Human Interleukin-31 mAb MT158; biotinylated
IL-31 is a 24 kD cytokine belonging to the IL-6 cytokine family. It is secreted by activated T cells, and memory T cells with capacity to produce IL-31 have been shown to be particularly abundant in the skin where they may contribute to inflammation. The receptor for IL-31 is found on e.g. keratinocytes, endothelial cells and can be upregulated on activated monocytes.
IL-31 is considered as a Th2 type cytokine but with different functions than IL-4, IL-5 and IL-13. In transgenic mice overexpressing IL-31, the cytokine induces pruritus and dermatitis resembling human atopic dermatitis (AD). In human, IL-31 has been associated with AD, atopic and contact allergies and airway hypersensitivity but also inflammatory bowel disease.
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| Monoclonal antibodies to Human IL-31 |
| Code |
Description |
Quantity |
Price |
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| 3530-6-250 |
Anti-Human Interleukin-31 mAb MT158; biotinylated |
250 µg |
1 800 SEK
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| Format: | Biotinylated. Supplied at 0.5 mg/ml. | | Application: | ELISpot (detection), ELISA (detection) | | Reactivity: | Human |
Mouse monoclonal antibody specific for human IL-31. Suitable as detection antibody in ELISA and ELISpot for detection of IL-31 in combination with mAbs MT31/88 (product code 3530-3).
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