Human IL-17A ELISpot PLUS kit (HRP)
Interleukin-17A (IL-17A) is a potent proinflammatory cytokine produced by activated Th17 (T-helper 17) cells and certain cells belonging to the innate immune system. Th17 cells play an important role in autoimmune diseases and protection against bacteria and fungi. IL-17A acts on a broad range of cell types to induce expression of cytokines, chemokines and metalloproteinases. As a result, secretion of IL-17A promotes inflammatory responses, which leads to the recruitment of neutrophils, enhancement of antibody production and activation of T cells. Increased expression of IL-17A is seen in autoimmune diseases such as multiple sclerosis and rheumatoid arthritis. It is also associated with asthma, psoriasis, cancer and transplant rejection.
Reacts with Human, cross-reacts with certain non-human primates. Please consult this comprehensive table for information about cross-reactivities with non-human primates.
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| Human IL-17A ELISpot PLUS kit incl. plates and substrate |
| Code |
Description |
Quantity |
Price |
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| 3520-2HW-Plus |
Human IL-17A ELISpot PLUS kit (HRP) |
4 x 96 |
5 100 SEK
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| Format: | Kit containing 4 plates, capture and detection antibodies, Streptavidin-HRP, TMB substrate and positive control. | | Application: | ELISpot | | Reactivity: | Human |
ELISpot PLUS kit for the detection of human IL-17A. This complete kit contains ELISpot plates with PVDF membrane, monoclonal capture antibody, monocl. biotin. detection antibody, Streptavidin-HRP, TMB substrate and anti-CD3 mAb as positive control.
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