Human IL-17A ELISpot kit (HRP)
Interleukin-17A (IL-17A) is a potent proinflammatory cytokine produced by activated Th17 (T-helper 17) cells and certain cells belonging to the innate immune system. Th17 cells play an important role in autoimmune diseases and protection against bacteria and fungi. IL-17A acts on a broad range of cell types to induce expression of cytokines, chemokines and metalloproteinases. As a result, secretion of IL-17A promotes inflammatory responses, which leads to the recruitment of neutrophils, enhancement of antibody production and activation of T cells. Increased expression of IL-17A is seen in autoimmune diseases such as multiple sclerosis and rheumatoid arthritis. It is also associated with asthma, psoriasis, cancer and transplant rejection.
Reacts with Human, cross-reacts with certain non-human primates. Please consult this comprehensive table for information about cross-reactivities with non-human primates.
|
| Human IL-17A ELISpot kit without plates |
| Code |
Description |
Quantity |
Price |
|
| 3520-2H |
Human IL-17A ELISpot kit (HRP) |
for 4 x 96 |
4 000 SEK
|
| Format: | Reagents sufficient for 4 ELISpot plates, Enzyme: HRP | | Application: | ELISpot | | Reactivity: | Reacts with Human, cross reacts with Common Marmoset. Inquire for reactivity with other Monkey species. |
Basic ELISpot kit for the detection of human IL-17A. The kit contains capture antibody, biotinylated detection antibody and Streptavidin-HRP.
|
|
 |
